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X-Chromosome Inactivation and Escape from X Inactivation in Mouse

X chromosome inactivation silences one X chromosome in female mammals. However, this silencing is incomplete, and some genes escape X inactivation. We describe methods to determine the chromosome- wide X inactivation status of genes in tissues or cell lines derived from mice using a combination of s...

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Bibliografiske detaljer
Udgivet i:Methods Mol Biol
Main Authors: Ma, Wenxiu, Bonora, Giancarlo, Berletch, Joel B., Deng, Xinxian, Noble, William S., Disteche, Christine M.
Format: Artigo
Sprog:Inglês
Udgivet: 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6269188/
https://ncbi.nlm.nih.gov/pubmed/30218369
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/978-1-4939-8766-5_15
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