Systematic Evaluation of Structure-Activity Relationships of the Riminophenazine Class and Discovery of a C2 Pyridylamino Series for the Treatment of Multidrug-Resistant Tuberculosis

Clofazimine, a member of the riminophenazine class of drugs, is the cornerstone agent for the treatment of leprosy. This agent is currently being studied in clinical trials for the treatment of multidrug-resistant tuberculosis to address the urgent need for new drugs that can overcome existing and e...

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Publicado no:Molecules
Main Authors: Liu, Binna, Liu, Kai, Lu, Yu, Zhang, Dongfeng, Yang, Tianming, Li, Xuan, Ma, Chen, Zheng, Meiqin, Wang, Bin, Zhang, Gang, Wang, Fei, Ma, Zhenkun, Li, Chun, Huang, Haihong, Yin, Dali
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2012
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6269036/
https://ncbi.nlm.nih.gov/pubmed/22510605
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules17044545
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