Synthesis and Biological Evaluation of Novel 2-Methoxypyridylamino-Substituted Riminophenazine Derivatives as Antituberculosis Agents

Clofazimine, a member of the riminophenazine class, is one of the few antibiotics that are still active against multidrug-resistant Mycobacterium tuberculosis (M. tuberculosis). However, the clinical utility of this agent is limited by its undesirable physicochemical properties and skin pigmentation...

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Udgivet i:Molecules
Main Authors: Zhang, Dongfeng, Liu, Yang, Zhang, Chunlin, Zhang, Hao, Wang, Bin, Xu, Jian, Fu, Lei, Yin, Dali, Cooper, Christopher B., Ma, Zhenkun, Lu, Yu, Huang, Haihong
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2014
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6271099/
https://ncbi.nlm.nih.gov/pubmed/24722591
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules19044380
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