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Practical Synthesis of Hydroxychromenes and Evaluation of Their Biological Activity
A simple and efficient seven steps synthesis of brodifacoum and difethialone from phenylacetyl chloride is described. The key synthetic strategies involve Friedel-Crafts acylation, intramolecular ring cyclization and condensation reaction in the presence of Brønsted-Lowry acids. It was found that br...
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| Publicado no: | Molecules |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
MDPI
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6269019/ https://ncbi.nlm.nih.gov/pubmed/22205090 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules17010240 |
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