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Catalytic Asymmetric Hydrogenation of 3-Substituted Benzisoxazoles

A variety of 3-substituted benzisoxazoles were reduced with hydrogen using the chiral ruthenium catalyst, {RuCl(p-cymene)[(R,R)-(S,S)-PhTRAP]}Cl. The ruthenium-catalyzed hydrogenation proceeded in high yield in the presence of an acylating agent, affording α-substituted o-hydroxybenzylamines with up...

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Detalhes bibliográficos
Publicado no:Molecules
Main Authors: Ikeda, Ryuhei, Kuwano, Ryoichi
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6268747/
https://ncbi.nlm.nih.gov/pubmed/22728365
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules17096901
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