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Catalytic Asymmetric Synthesis of Cyclohexanes by Hydrogen Borrowing Annulations

Hydrogen borrowing catalysis serves as a powerful alternative to enolate alkylation, enabling the direct coupling of ketones with unactivated alcohols. However, to date, methods that enable control over the absolute stereochemical outcome of such a process have remained elusive. Here we report a cat...

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Detalhes bibliográficos
Publicado no:Angew Chem Int Ed Engl
Main Authors: Armstrong, Roly J., Akhtar, Wasim M., Young, Tom A., Duarte, Fernanda, Donohoe, Timothy J.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6771629/
https://ncbi.nlm.nih.gov/pubmed/31265208
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201907514
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