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Design and Synthesis of an (18)F-Labeled Version of Phenylethyl Orvinol ([(18)F]FE-PEO) for PET-Imaging of Opioid Receptors

The semisynthetic oripavine derivative phenethyl orvinol (PEO), a full agonist at opioid receptors (OR), is an attractive structural motif for developing (18)F-labeled PET tracers with a high degree of sensitivity for competition between endogenous and exogenous OR-ligands. The target cold reference...

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Detalhes bibliográficos
Publicado no:Molecules
Main Authors: Marton, János, Henriksen, Gjermund
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6268392/
https://ncbi.nlm.nih.gov/pubmed/23023682
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules171011554
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