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A New and Efficient Method for the Synthesis of 3,4-Disubstituted Pyrrolidine-2,5-diones

A newly found reaction for the synthesis of 3,4-disubstituted 1-hydroxy-pyrrolidine-2,5-diones from 3-substituted coumarins and nitromethane has been elaborated. The reaction involved a simple and convenient experimental procedure. The applicability of the rearrangement reaction is determined.

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Detalhes bibliográficos
Publicado no:Molecules
Main Authors: Ilieva, Eleonora D., Petkova, Nevena I., Nikolova, Rositca D.
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6268139/
https://ncbi.nlm.nih.gov/pubmed/22547316
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules17054936
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