A phase II study of NK012, a polymeric micelle formulation of SN-38, in unresectable, metastatic or recurrent colorectal cancer patients

PURPOSE: NK012 is a polymeric micelle formulation of SN-38, the active metabolite of irinotecan. We evaluated the efficacy and safety of NK012 in Japanese patients with unresectable metastatic colorectal cancer. METHODS: We conducted a multicenter open-label phase II trial of NK012 monotherapy in 58...

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Publicado en:Cancer Chemother Pharmacol
Main Authors: Hamaguchi, Tetsuya, Tsuji, Akihito, Yamaguchi, Kensei, Takeda, Koji, Uetake, Hiroyuki, Esaki, Taito, Amagai, Kenji, Sakai, Daisuke, Baba, Hideo, Kimura, Masami, Matsumura, Yasuhiro, Tsukamoto, Tetsuji
Formato: Artigo
Idioma:Inglês
Publicado: Springer Berlin Heidelberg 2018
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Original Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6267673/
https://ncbi.nlm.nih.gov/pubmed/30284603
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00280-018-3693-6
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