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A phase II study of NK012, a polymeric micelle formulation of SN-38, in unresectable, metastatic or recurrent colorectal cancer patients
PURPOSE: NK012 is a polymeric micelle formulation of SN-38, the active metabolite of irinotecan. We evaluated the efficacy and safety of NK012 in Japanese patients with unresectable metastatic colorectal cancer. METHODS: We conducted a multicenter open-label phase II trial of NK012 monotherapy in 58...
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| Publicat a: | Cancer Chemother Pharmacol |
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| Autors principals: | , , , , , , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Springer Berlin Heidelberg
2018
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6267673/ https://ncbi.nlm.nih.gov/pubmed/30284603 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00280-018-3693-6 |
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