Ribonuclease MCPiP1 contributes to the loss of micro-RNA-200 family members in pancreatic cancer cells

The microRNA-200 (miR-200) family is frequently down-regulated in tumors, including pancreatic adenocarcinomas (PDACs). In this study we have examined the mechanisms involved in the loss of miR-200s in tumoral pancreatic cells. Whereas miR-200 gene promoters appear methylated in mature miR-200 defic...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Boudouresque, Françoise, Siret, Carole, Dobric, Aurélie, Silvy, Françoise, Soubeyran, Philippe, Iovanna, Juan, Lombardo, Dominique, Berthois, Yolande
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2018
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6267598/
https://ncbi.nlm.nih.gov/pubmed/30542509
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.26310
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