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Docoxahexaenoic Acid Induces Apoptosis of Pancreatic Cancer Cells by Suppressing Activation of STAT3 and NF-κB

The ω3-polyunsaturated fatty acid docosahexenoic acid (DHA) is known to induce apoptosis of cancer cells. In this study, DHA was shown to reduce viability of pancreatic cancer cells (PANC-1) by inducing DNA fragmentation, activating caspase-3, and increasing the ratio of Bax/Bcl-2. To determine the...

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Detalhes bibliográficos
Publicado no:Nutrients
Main Authors: Park, Mirae, Lim, Joo Weon, Kim, Hyeyoung
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6267441/
https://ncbi.nlm.nih.gov/pubmed/30400136
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/nu10111621
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