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Intronic miR-744 Inhibits Glioblastoma Migration by Functionally Antagonizing Its Host Gene MAP2K4

Background: The second intron of Mitogen-Activated Protein Kinase Kinase 4 (MAP2K4), an important hub in the pro-invasive MAPK pathway, harbors miR-744. There is accumulating evidence that intronic micro-RNAs (miRNAs) are capable of either supporting or restraining functional pathways of their host...

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Detalhes bibliográficos
Publicado no:Cancers (Basel)
Main Authors: Hübner, Max, Hinske, Christian Ludwig, Effinger, David, Wu, Tingting, Thon, Niklas, Kreth, Friedrich-Wilhelm, Kreth, Simone
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6266622/
https://ncbi.nlm.nih.gov/pubmed/30366472
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers10110400
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