Delayed LY333013 (Oral) and LY315920 (Intravenous) Reverse Severe Neurotoxicity and Rescue Juvenile Pigs from Lethal Doses of Micrurus fulvius (Eastern Coral Snake) Venom

There is a clear, unmet need for effective, lightweight, shelf-stable and economical snakebite envenoming therapies that can be given rapidly after the time of a snake’s bite and as adjuncts to antivenom therapies in the hospital setting. The sPLA2 inhibitor, LY315920, and its orally bioavailable pr...

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Dettagli Bibliografici
Pubblicato in:Toxins (Basel)
Autori principali: Lewin, Matthew R., Gilliam, Lyndi L., Gilliam, John, Samuel, Stephen P., Bulfone, Tommaso C., Bickler, Philip E., Gutiérrez, José María
Natura: Artigo
Lingua:Inglês
Pubblicazione: MDPI 2018
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6265968/
https://ncbi.nlm.nih.gov/pubmed/30453607
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/toxins10110479
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