Transcription Factor Eb Is Required for Macropinocytosis-Mediated Growth Recovery of Nutrient-Deprived Kras-Mutant Cells

Macropinocytosis is a regulated form of endocytosis that mediates the nonselective uptake of nutrients to support growth under nutrient-deprived conditions. KRAS-mutant cancer cells upregulate macropinocytosis to import extracellular proteins, which subsequently undergo proteolytic degradation in th...

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Bibliographic Details
Published in:Nutrients
Main Authors: Jeong, Seokmin, Byun, Jun-Kyu, Cho, Sung Jin, Chin, Jungwook, Lee, In-Kyu, Choi, Yeon-Kyung, Park, Keun-Gyu
Format: Artigo
Language:Inglês
Published: MDPI 2018
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6265907/
https://ncbi.nlm.nih.gov/pubmed/30400219
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/nu10111638
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