Cyclopeptide RA-V Inhibits Organ Enlargement and Tumorigenesis Induced by YAP Activation

The Hippo pathway restricts organ size during development and its inactivation plays a crucial role in cancer. Yes-associated protein (YAP) and its paralog transcriptional coactivator with PSD-95/Dlg/ZO-1 (PDZ)-binding motif (TAZ) are transcription co-activators and effectors of the Hippo pathway me...

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Detalhes bibliográficos
Publicado no:Cancers (Basel)
Main Authors: Ji, Xinyan, Song, Lihua, Sheng, Li, Gao, Anhui, Zhao, Yang, Han, Shixun, Zhang, Yuchao, Zhu, Chu, Zhao, Simeng, Wang, Zhe, Xu, Bohan, Li, Li, Li, Jia, Tan, Ninghua, Zhao, Bin
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6265802/
https://ncbi.nlm.nih.gov/pubmed/30453531
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers10110449
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