Differential analysis of chromatin accessibility and histone modifications for predicting mouse developmental enhancers

Enhancers are distal cis-regulatory elements that modulate gene expression. They are depleted of nucleosomes and enriched in specific histone modifications; thus, calling DNase-seq and histone mark ChIP-seq peaks can predict enhancers. We evaluated nine peak-calling algorithms for predicting enhance...

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Dettagli Bibliografici
Pubblicato in:Nucleic Acids Res
Autori principali: Fu, Shaliu, Wang, Qin, Moore, Jill E, Purcaro, Michael J, Pratt, Henry E, Fan, Kaili, Gu, Cuihua, Jiang, Cizhong, Zhu, Ruixin, Kundaje, Anshul, Lu, Aiping, Weng, Zhiping
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2018
Soggetti:
Gene regulation, Chromatin and Epigenetics
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6265487/
https://ncbi.nlm.nih.gov/pubmed/30137428
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gky753
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