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NMR structure of a G-quadruplex formed by four d(G(4)C(2)) repeats: insights into structural polymorphism
Most frequent genetic cause of amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD), is a largely increased number of d(G(4)C(2))n•(G(2)C(4))n repeats located in the non-coding region of C9orf72 gene. Non-canonical structures, including G-quadruplexes, formed within expanded repeats...
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| Publicado no: | Nucleic Acids Res |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6265483/ https://ncbi.nlm.nih.gov/pubmed/30277522 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gky886 |
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