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The Inner Ear Heat Shock Transcriptional Signature Identifies Compounds That Protect Against Aminoglycoside Ototoxicity

Mechanosensory hair cells of the inner ear transduce auditory and vestibular sensory input. Hair cells are susceptible to death from a variety of stressors, including treatment with therapeutic drugs that have ototoxic side effects. There is a need for co-therapies to mitigate drug-induced ototoxici...

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Detalhes bibliográficos
Publicado no:Front Cell Neurosci
Main Authors: Ryals, Matthew, Morell, Robert J., Martin, Daniel, Boger, Erich T., Wu, Patricia, Raible, David W., Cunningham, Lisa L.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6265442/
https://ncbi.nlm.nih.gov/pubmed/30532693
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fncel.2018.00445
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