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The Inner Ear Heat Shock Transcriptional Signature Identifies Compounds That Protect Against Aminoglycoside Ototoxicity

Mechanosensory hair cells of the inner ear transduce auditory and vestibular sensory input. Hair cells are susceptible to death from a variety of stressors, including treatment with therapeutic drugs that have ototoxic side effects. There is a need for co-therapies to mitigate drug-induced ototoxici...

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Bibliografske podrobnosti
izdano v:Front Cell Neurosci
Main Authors: Ryals, Matthew, Morell, Robert J., Martin, Daniel, Boger, Erich T., Wu, Patricia, Raible, David W., Cunningham, Lisa L.
Format: Artigo
Jezik:Inglês
Izdano: Frontiers Media S.A. 2018
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6265442/
https://ncbi.nlm.nih.gov/pubmed/30532693
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fncel.2018.00445
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