Test-retest reliability and convergent validity of (R)-[(11)C]PK11195 outcome measures without arterial input function

PURPOSE: The PET radioligand (R)-[(11)C]PK11195 is used to quantify the 18-kDa translocator protein (TSPO), a marker for glial activation. Since there is no brain region devoid of TSPO, an arterial input function (AIF) is ideally required for quantification of binding. However, obtaining an AIF is e...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:EJNMMI Res
Prif Awduron: Plavén-Sigray, Pontus, Matheson, Granville James, Cselényi, Zsolt, Jucaite, Aurelija, Farde, Lars, Cervenka, Simon
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Springer Berlin Heidelberg 2018
Pynciau:
Original Research
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6265355/
https://ncbi.nlm.nih.gov/pubmed/30498919
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13550-018-0455-8
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