Test-retest reliability and convergent validity of (R)-[(11)C]PK11195 outcome measures without arterial input function

PURPOSE: The PET radioligand (R)-[(11)C]PK11195 is used to quantify the 18-kDa translocator protein (TSPO), a marker for glial activation. Since there is no brain region devoid of TSPO, an arterial input function (AIF) is ideally required for quantification of binding. However, obtaining an AIF is e...

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Bibliografiska uppgifter
I publikationen:EJNMMI Res
Huvudupphovsmän: Plavén-Sigray, Pontus, Matheson, Granville James, Cselényi, Zsolt, Jucaite, Aurelija, Farde, Lars, Cervenka, Simon
Materialtyp: Artigo
Språk:Inglês
Publicerad: Springer Berlin Heidelberg 2018
Ämnen:
Original Research
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC6265355/
https://ncbi.nlm.nih.gov/pubmed/30498919
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13550-018-0455-8
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