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Evolution of a General RNA-Cleaving FANA Enzyme

The isolation of synthetic genetic polymers (XNAs) with catalytic activity demonstrates that catalysis is not limited to natural biopolymers, but it remains unknown whether such systems can achieve robust catalysis with Michaelis-Menten kinetics. Here, we describe an efficient RNA-cleaving 2’-fluoro...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Wang, Yajun, Ngor, Arlene K., Nikoomanzar, Ali, Chaput, John C.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6265334/
https://ncbi.nlm.nih.gov/pubmed/30498223
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-07611-1
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