Broadened immunity against influenza by vaccination with computationally designed influenza virus N1 neuraminidase constructs

Split inactivated influenza vaccines remain one of the primary preventative strategies against severe influenza disease in the population. However, current vaccines are only effective against a limited number of matched strains. The need for broadly protective vaccines is acute due to the high mutat...

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Bibliografiske detaljer
Udgivet i:NPJ Vaccines
Main Authors: Job, E. R., Ysenbaert, T., Smet, A., Christopoulou, I., Strugnell, T., Oloo, E. O., Oomen, R. P., Kleanthous, H., Vogel, T. U., Saelens, X.
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2018
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6265323/
https://ncbi.nlm.nih.gov/pubmed/30510776
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41541-018-0093-1
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