The immunologic constant of rejection classification refines the prognostic value of conventional prognostic signatures in breast cancer

BACKGROUND: The immunologic constant of rejection (ICR) is a broad phenomenon of Th-1 immunity-mediated, tissue-specific destruction. METHODS: We tested the prognostic value of a 20-gene ICR expression signature in 8766 early breast cancers. RESULTS: Thirty-three percent of tumours were ICR1, 29% IC...

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Udgivet i:Br J Cancer
Main Authors: Bertucci, François, Finetti, Pascal, Simeone, Ines, Hendrickx, Wouter, Wang, Ena, Marincola, Francesco M., Viens, Patrice, Mamessier, Emilie, Ceccarelli, Michele, Birnbaum, Daniel, Bedognetti, Davide
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2018
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6265245/
https://ncbi.nlm.nih.gov/pubmed/30353048
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41416-018-0309-1
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