Complementary Wnt Sources Regulate Lymphatic Vascular Development via PROX1-Dependent Wnt/β-Catenin Signaling

Wnt/β-catenin signaling is necessary for lymphatic vascular development. Oscillatory shear stress (OSS) enhances Wnt/β-catenin signaling in cultured lymphatic endothelial cells (LECs) to induce expression of the lymphedema-associated transcription factors GATA2 and FOXC2. However, the mechanisms by...

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Vydáno v:Cell Rep
Hlavní autoři: Cha, Boksik, Geng, Xin, Mahamud, Md. Riaj, Zhang, Jenny Y., Chen, Lijuan, Kim, Wantae, Jho, Eek-hoon, Kim, Yeunhee, Choi, Dongwon, Dixon, J. Brandon, Chen, Hong, Hong, Young-Kwon, Olson, Lorin, Kim, Tae Hoon, Merrill, Bradley J., Davis, Michael J., Srinivasan, R. Sathish
Médium: Artigo
Jazyk:Inglês
Vydáno: 2018
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6264919/
https://ncbi.nlm.nih.gov/pubmed/30332639
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2018.09.049
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