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Docking Studies and α-Substitution Effects on the Anti-Inflammatory Activity of β-Hydroxy-β-arylpropanoic Acids

Six β-hydroxy-β-aryl propanoic acids were synthesised using a modification of Reformatsky reaction which has already been reported. These acids belong to the aryl propanoic acid class of compounds, structurally similar to the NSAIDs, such as ibuprofen, and an anti-inflammatory activity is thus expec...

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Publicat a:Molecules
Autors principals: Savić, Jelena S., Dilber, Sanda P., Marković, Bojan D., Milenković, Marina T., Vladimirov, Sote M., Juranić, Ivan O.
Format: Artigo
Idioma:Inglês
Publicat: MDPI 2011
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6264771/
https://ncbi.nlm.nih.gov/pubmed/25134768
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules16086645
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