Synthesis, biological evaluation and in silico molecular docking of novel 1-hydroxy-naphthyl substituted heterocycles

The versatile precursor 2-acetyl-4-allyl-1-hydroxy naphthalene was synthesized efficiently via Claisen rearrangement 2-acetyl-1-allyloxynaphthalene. The Claisen-Schmidt condensation of latter precursor afforded the corresponding chalcones which were exploited to synthesize a series of potential hete...

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Dettagli Bibliografici
Pubblicato in:Saudi Pharm J
Autori principali: El-Desoky, El-Sayed I., Keshk, Eman M., El-Sawi, Aya A., Abozeid, Mohamed A., Abouzeid, Laila A., Abdel-Rahman, Abdel-Rahman H.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Elsevier 2018
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Original Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6128714/
https://ncbi.nlm.nih.gov/pubmed/30202227
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jsps.2018.03.013
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