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Regularizing firing patterns of rat subthalamic neurons ameliorates parkinsonian motor deficits

The subthalamic nucleus (STN) is an effective therapeutic target for deep brain stimulation (DBS) for Parkinson’s disease (PD), and histamine levels are elevated in the basal ganglia in PD patients. However, the effect of endogenous histaminergic modulation on STN neuronal activities and the neurona...

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Detalles Bibliográficos
Publicado en:J Clin Invest
Main Authors: Zhuang, Qian-Xing, Li, Guang-Ying, Li, Bin, Zhang, Chang-Zheng, Zhang, Xiao-Yang, Xi, Kang, Li, Hong-Zhao, Wang, Jian-Jun, Zhu, Jing-Ning
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Clinical Investigation 2018
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6264721/
https://ncbi.nlm.nih.gov/pubmed/30226827
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI99986
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