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Deranged NMDAergic cortico-subthalamic transmission underlies parkinsonian motor deficits
Parkinson’s disease (PD) is the most prevalent hypokinetic movement disorder, and symptomatic PD pathogenesis has been ascribed to imbalances between the direct and indirect pathways in the basal ganglia circuitry. Here, we applied glutamate receptor blockers to the subthalamic nucleus (STN) of park...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
American Society for Clinical Investigation
2014
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4191009/ https://ncbi.nlm.nih.gov/pubmed/25202982 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI75587 |
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