HIC1 deletion promotes breast cancer progression by activating tumor cell/fibroblast crosstalk

Breast cancer (BrCa) is the malignant tumor that most seriously threatens female health; however, the molecular mechanism underlying its progression remains unclear. Here, we found that conditional deletion of hypermethylated in cancer 1 (HIC1) in the mouse mammary gland might contribute to premalig...

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Detalhes bibliográficos
Publicado no:J Clin Invest
Main Authors: Wang, Yingying, Weng, Xiaoling, Wang, Luoyang, Hao, Mingang, Li, Yue, Hou, Lidan, Liang, Yu, Wu, Tianqi, Yao, Mengfei, Lin, Guowen, Jiang, Yiwei, Fu, Guohui, Hou, Zhaoyuan, Meng, Xiangjun, Lu, Jinsong, Wang, Jianhua
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2018
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6264654/
https://ncbi.nlm.nih.gov/pubmed/30204129
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI99974
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