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Crosstalk among proteome, acetylome and succinylome in colon cancer HCT116 cell treated with sodium dichloroacetate

Protein lysine acetylation and succinylation play important regulatory roles in cells, both of which or each other has a close relationship. Dichloroacetate (DCA), a well-known pyruvate dehydrogenase kinase (PDK) inhibitor, has the potential to be used as anti-cancer drugs for several tumors includi...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Zhu, Danxi, Hou, Lidan, Hu, Bin, Zhao, Hang, Sun, Jie, Wang, Jianhua, Meng, Xiangjun
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5118697/
https://ncbi.nlm.nih.gov/pubmed/27874079
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep37478
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