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Crosstalk among proteome, acetylome and succinylome in colon cancer HCT116 cell treated with sodium dichloroacetate

Protein lysine acetylation and succinylation play important regulatory roles in cells, both of which or each other has a close relationship. Dichloroacetate (DCA), a well-known pyruvate dehydrogenase kinase (PDK) inhibitor, has the potential to be used as anti-cancer drugs for several tumors includi...

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Bibliografski detalji
Izdano u:Sci Rep
Glavni autori: Zhu, Danxi, Hou, Lidan, Hu, Bin, Zhao, Hang, Sun, Jie, Wang, Jianhua, Meng, Xiangjun
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group 2016
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5118697/
https://ncbi.nlm.nih.gov/pubmed/27874079
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep37478
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