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Osteopontin controls immunosuppression in the tumor microenvironment

Cancer cells evade the immune system through a variety of different mechanisms, including the inhibition of antitumor effector T cells via checkpoint ligand–receptor interaction. Moreover, studies have shown that blocking these checkpoint pathways can reinvigorate the antitumor immunity, thereby pro...

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Bibliografiske detaljer
Udgivet i:J Clin Invest
Hovedforfatter: Shurin, Michael R.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Clinical Investigation 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6264653/
https://ncbi.nlm.nih.gov/pubmed/30395537
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI124918
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