A Curcumin Derivative, 2,6-Bis(2,5-dimethoxybenzylidene)-cyclohexanone (BDMC33) Attenuates Prostaglandin E(2) Synthesis via Selective Suppression of Cyclooxygenase-2 in IFN-γ/LPS-Stimulated Macrophages

Our preliminary screening had shown that the curcumin derivative [2,6-bis(2,5-dimethoxybenzylidene)cyclohexanone] or BDMC33 exhibited improved anti-inflammatory activity by inhibiting nitric oxide synthesis in activated macrophage cells. In this study, we further investigated the anti-inflammatory p...

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Detalhes bibliográficos
Publicado no:Molecules
Main Authors: Lee, Ka-Heng, Abas, Faridah, Alitheen, Noorjahan Banu Mohamed, Shaari, Khozirah, Lajis, Nordin Haji, Ahmad, Syahida
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2011
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6264440/
https://ncbi.nlm.nih.gov/pubmed/22113581
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules16119728
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