BDMC33, A Curcumin Derivative Suppresses Inflammatory Responses in Macrophage-Like Cellular System: Role of Inhibition in NF-κB and MAPK Signaling Pathways

Our preliminary screening has shown that curcumin derivative BDMC33 [2,6-bis(2,5-dimethoxybenzylidene)cyclohexanone] exerted promising nitric oxide inhibitory activity in activated macrophages. However, the molecular basis and mechanism for its pharmacological action is yet to be elucidated. The aim...

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Main Authors: Lee, Ka-Heng, Chow, Yuh-Lit, Sharmili, Vidyadaran, Abas, Faridah, Alitheen, Noorjahan Banu Mohamed, Shaari, Khozirah, Israf, Daud Ahmad, Lajis, Nordin Haji, Syahida, Ahmad
Formato: Artigo
Idioma:Inglês
Publicado em: Molecular Diversity Preservation International (MDPI) 2012
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3317699/
https://ncbi.nlm.nih.gov/pubmed/22489138
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms13032985
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