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Direct Enzymatic Route for the Preparation of Novel Enantiomerically Enriched Hydroxylated β-Amino Ester Stereoisomers

Enantiomerically enriched hydroxy-substituted β-amino esters have been synthesized through CAL-B-catalyzed enantioselective hydrolysis in organic media. Moderate to good enantiomeric excess values (ee ≥ 52%) were obtained when the CAL-B-catalyzed reactions were performed in t-BuOMe, at 60 ºC with 0....

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Detalhes bibliográficos
Publicado no:Molecules
Main Authors: Forró, Enikő, Schönstein, László, Kiss, Loránd, Vega-Peñaloza, Alberto, Juaristi, Eusebio, Fülöp, Ferenc
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6264416/
https://ncbi.nlm.nih.gov/pubmed/20657421
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules15063998
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