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Synthesis of highly functionalized β-aminocyclopentanecarboxylate stereoisomers by reductive ring opening reaction of isoxazolines

A rapid and simple procedure was devised for the synthesis of multifunctionalized cyclic β-amino esters and γ-amino alcohols via the 1,3-dipolar cycloaddition of nitrile oxides to β-aminocyclopentenecarboxylates. The opening of the isoxazoline reductive ring to the corresponding highly functionalize...

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Bibliografske podrobnosti
Main Authors: Nonn, Melinda, Kiss, Loránd, Sillanpää, Reijo, Fülöp, Ferenc
Format: Artigo
Jezik:Inglês
Izdano: Beilstein-Institut 2012
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3302068/
https://ncbi.nlm.nih.gov/pubmed/22423276
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3762/bjoc.8.10
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