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Synthesis and Antimalarial Activity of Novel Dihydro-Artemisinin Derivatives

The Plasmodium falciparum cysteine protease falcipain-2, one of the most promising targets for antimalarial drug design, plays a key role in parasite survival as a major peptide hydrolase within the hemoglobin degradation pathway. In this work, a series of novel dihydroartemisinin derivatives based...

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Detalhes bibliográficos
Publicado no:Molecules
Main Authors: Liu, Yang, Cui, Kunqiang, Lu, Weiqiang, Luo, Wei, Wang, Jian, Huang, Jin, Guo, Chun
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6264262/
https://ncbi.nlm.nih.gov/pubmed/21629181
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules16064527
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