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Synthesis and Antimalarial Activity of Novel Dihydro-Artemisinin Derivatives
The Plasmodium falciparum cysteine protease falcipain-2, one of the most promising targets for antimalarial drug design, plays a key role in parasite survival as a major peptide hydrolase within the hemoglobin degradation pathway. In this work, a series of novel dihydroartemisinin derivatives based...
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Publicado no: | Molecules |
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Main Authors: | , , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
MDPI
2011
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6264262/ https://ncbi.nlm.nih.gov/pubmed/21629181 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules16064527 |
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