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Schiff Bases of Indoline-2,3-dione: Potential Novel Inhibitors of Mycobacterium Tuberculosis (Mtb) DNA Gyrase (†)

In the present study a series of Schiff bases of indoline-2,3-dione were synthesized and investigated for their Mtb gyrase inhibitory activity. Promising inhibitory activity was demonstrated with some of these derivatives, which exhibited IC(50) values ranging from 50–157 μM. The orientation and the...

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Bibliografische gegevens
Gepubliceerd in:Molecules
Hoofdauteurs: Aboul-Fadl, Tarek, Abdel-Aziz, Hatem A., Abdel-Hamid, Mohammed K., Elsaman, Tilal, Thanassi, Jane, Pucci, Michael J.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: MDPI 2011
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6264139/
https://ncbi.nlm.nih.gov/pubmed/22143547
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules16097864
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