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A discontinuous Galerkin model for fluorescence loss in photobleaching of intracellular polyglutamine protein aggregates

BACKGROUND: Intracellular phase separation and aggregation of proteins with extended poly-glutamine (polyQ) stretches are hallmarks of various age-associated neurodegenerative diseases. Progress in our understanding of such processes heavily relies on quantitative fluorescence imaging of suitably ta...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:BMC Biophys
Prif Awduron: Hansen, Christian V., Schroll, Hans J., Wüstner, Daniel
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: BioMed Central 2018
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6264036/
https://ncbi.nlm.nih.gov/pubmed/30519460
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13628-018-0046-0
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