Genomics of response to immune checkpoint therapies for cancer: implications for precision medicine

Immune checkpoint blockade (ICB) therapies, which potentiate the body’s natural immune response against tumor cells, have shown immense promise in the treatment of various cancers. Currently, tumor mutational burden (TMB) and programmed death ligand 1 (PD-L1) expression are the primary biomarkers ev...

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Kaydedildi:
Detaylı Bibliyografya
Yayımlandı:Genome Med
Asıl Yazarlar: Conway, Jake R., Kofman, Eric, Mo, Shirley S., Elmarakeby, Haitham, Van Allen, Eliezer
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: BioMed Central 2018
Konular:
Review
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6264032/
https://ncbi.nlm.nih.gov/pubmed/30497521
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13073-018-0605-7
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