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Chaos synchronization and Nelder-Mead search for parameter estimation in nonlinear pharmacological systems: estimating tumor antigenicity in a model of immunotherapy

In mathematical pharmacology, models are constructed to confer a robust method for optimizing treatment. The predictive capability of pharmacological models depends heavily on the ability to track the system and to accurately determine parameters with reference to the sensitivity in projected outcom...

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Dettagli Bibliografici
Pubblicato in:Prog Biophys Mol Biol
Autori principali: Pillai, Nikhil, Craig, Morgan, Dokoumetzidis, Aristeidis, Schwartz, Sorell L, Bies, Robert, Freedman, Immanuel
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2018
Soggetti:
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6263737/
https://ncbi.nlm.nih.gov/pubmed/29928905
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.pbiomolbio.2018.06.006
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