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Chaos synchronization and Nelder-Mead search for parameter estimation in nonlinear pharmacological systems: estimating tumor antigenicity in a model of immunotherapy

In mathematical pharmacology, models are constructed to confer a robust method for optimizing treatment. The predictive capability of pharmacological models depends heavily on the ability to track the system and to accurately determine parameters with reference to the sensitivity in projected outcom...

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Detalhes bibliográficos
Publicado no:Prog Biophys Mol Biol
Main Authors: Pillai, Nikhil, Craig, Morgan, Dokoumetzidis, Aristeidis, Schwartz, Sorell L, Bies, Robert, Freedman, Immanuel
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6263737/
https://ncbi.nlm.nih.gov/pubmed/29928905
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.pbiomolbio.2018.06.006
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