Time series analysis of neoadjuvant chemotherapy and bevacizumab-treated breast carcinomas reveals a systemic shift in genomic aberrations

BACKGROUND: Chemotherapeutic agents such as anthracyclines and taxanes are commonly used in the neoadjuvant setting. Bevacizumab is an antibody which binds to vascular endothelial growth factor A (VEGFA) and inhibits its receptor interaction, thus obstructing the formation of new blood vessels. METH...

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Publicat a:Genome Med
Autors principals: Höglander, Elen Kristine, Nord, Silje, Wedge, David C., Lingjærde, Ole Christian, Silwal-Pandit, Laxmi, Gythfeldt, Hedda vdL, Vollan, Hans Kristian Moen, Fleischer, Thomas, Krohn, Marit, Schlitchting, Ellen, Borgen, Elin, Garred, Øystein, Holmen, Marit M., Wist, Erik, Naume, Bjørn, Van Loo, Peter, Børresen-Dale, Anne-Lise, Engebraaten, Olav, Kristensen, Vessela
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2018
Matèries:
Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6262977/
https://ncbi.nlm.nih.gov/pubmed/30497530
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13073-018-0601-y
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