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Ectopic Hedgehog Signaling Causes Cleft Palate and Defective Osteogenesis
Cleft palate is a common birth defect that frequently occurs in human congenital malformations caused by mutations in components of the Sonic Hedgehog (SHH) signaling cascade. Shh is expressed in dynamic, spatiotemporal domains within epithelial rugae and plays a key role in driving epithelial-mesen...
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| Publicado no: | J Dent Res |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
SAGE Publications
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6262265/ https://ncbi.nlm.nih.gov/pubmed/29975848 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/0022034518785336 |
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