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Regulation of Epstein-Barr Virus Life Cycle and Cell Proliferation by Histone H3K27 Methyltransferase EZH2 in Akata Cells

Epigenetic modifications play a pivotal role in the expression of the genes of Epstein-Barr virus (EBV). We found that de novo EBV infection of primary B cells caused moderate induction of enhancer of zeste homolog 2 (EZH2), the major histone H3 lysine 27 (K27) methyltransferase. To investigate the...

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Detalhes bibliográficos
Publicado no:mSphere
Main Authors: Ichikawa, Takaya, Okuno, Yusuke, Sato, Yoshitaka, Goshima, Fumi, Yoshiyama, Hironori, Kanda, Teru, Kimura, Hiroshi, Murata, Takayuki
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6262262/
https://ncbi.nlm.nih.gov/pubmed/30487153
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mSphere.00478-18
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