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The Epstein-Barr Virus BRRF1 Gene Is Dispensable for Viral Replication in HEK293 cells and Transformation

The Epstein-Barr virus (EBV) is a gamma-herpesvirus associated with several malignancies. It establishes a latent infection in B lymphocytes and is occasionally reactivated to enter the lytic cycle. Here we examined the role of the EBV gene BRRF1, which is expressed in the lytic state. We first conf...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Yoshida, Masahiro, Watanabe, Takahiro, Narita, Yohei, Sato, Yoshitaka, Goshima, Fumi, Kimura, Hiroshi, Murata, Takayuki
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5519699/
https://ncbi.nlm.nih.gov/pubmed/28729695
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-06413-7
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