Inhibition of spinal p38 MAPK prevents articular neutrophil infiltration in experimental arthritis via sympathetic activation

The central nervous system controls the innate immunity by modulating efferent neuronal networks. Recently, we have reported that central brain stimulation inhibits inflammatory responses. In the present study, we investigate whether spinal p38 mitogen-activated protein kinase (MAPK) affects joint i...

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Veröffentlicht in:Fundam Clin Pharmacol
Hauptverfasser: Kanashiro, Alexandre, Franchin, Marcelo, Bassi, Gabriel Shimizu, Santana, Dênis Augusto Reis, Cunha, Thiago Mattar, Cunha, Fernando Queiróz, Ulloa, Luis, Rodrigues, Gerson Jonathan
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2017
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6262227/
https://ncbi.nlm.nih.gov/pubmed/29206314
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/fcp.12338
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