Chronic Sleep Disruption Advances the Temporal Progression of Tauopathy in P301S Mutant Mice

Brainstem locus ceruleus neurons (LCn) are among the first neurons across the lifespan to evidence tau pathology, and LCn are implicated in tau propagation throughout the cortices. Yet, events influencing LCn tau are poorly understood. Activated persistently across wakefulness, LCn experience signif...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Zhu, Yan, Zhan, Guanxia, Fenik, Polina, Brandes, Madison, Bell, Patrick, Francois, Noelle, Shulman, Katherine, Veasey, Sigrid
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2018
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6262148/
https://ncbi.nlm.nih.gov/pubmed/30322903
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.0275-18.2018
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