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Characterization of human mosaic Rett syndrome brain tissue by single-nucleus RNA sequencing
In females with X-linked genetic disorders, wild-type and mutant cells coexist within brain tissue because of X-chromosome inactivation, posing challenges for interpreting the effects of X-linked mutant alleles on gene expression. We present a single-nucleus RNA sequencing approach that resolves mos...
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| Yayımlandı: | Nat Neurosci |
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| Asıl Yazarlar: | , , , , , , , , |
| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
2018
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6261686/ https://ncbi.nlm.nih.gov/pubmed/30455458 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41593-018-0270-6 |
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