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Mitochondria-targeted hydrogen sulfide donor AP39 improves neurological outcomes after cardiac arrest in mice

AIMS: Mitochondria-targeted hydrogen sulfide donor AP39, [(10-oxo-10-(4-(3-thioxo-3H-1,2-dithiol-5yl)phenoxy)decyl) triphenylphosphonium bromide], exhibits cytoprotective effects against oxidative stress in vitro. We examined whether or not AP39 improves neurological function and long term survival...

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Bibliografiske detaljer
Udgivet i:Nitric Oxide
Main Authors: Ikeda, Kohei, Marutani, Eizo, Hirai, Shuichi, Wood, Mark E., Whiteman, Matthew, Ichinose, Fumito
Format: Artigo
Sprog:Inglês
Udgivet: 2015
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6261663/
https://ncbi.nlm.nih.gov/pubmed/25960429
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.niox.2015.05.001
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